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When serological tests for syphilis became available, patients with AR pupils usually tested positive for syphilis. The AR pupil was named after Douglas Moray Cooper Lamb Argyll Robertson, a Scottish ophthalmologist who noted the association with syphilis in 1869. There is continued interest in the underlying pathophysiology, but the scarcity of cases makes ongoing research difficult. A video of AR pupils and light-near dissociation is available at ĪR pupils are extremely uncommon in the developed world. Pupils that “accommodate but do not react” are said to show light-near dissociation. They are a highly specific sign of neurosyphilis. They were formerly known as "prostitute's pupils" because of their association with syphilis and because, like a prostitute, they “accommodate but do not react.” ). OverviewĪrgyll Robertson pupils (“AR pupils”) are bilateral small pupils that constrict when the patient focuses on a near object (they “ accommodate” with near vision), but do not constrict when exposed to bright light (they do not “react” to light). List of terms related to Argyll Robertson pupilĮditor-In-Chief: C. Risk calculators and risk factors for Argyll Robertson pupilĬauses & Risk Factors for Argyll Robertson pupilĭiagnostic studies for Argyll Robertson pupilĪrgyll Robertson pupil in the Marketplace

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